Truth#

missionbio.demultiplex.dna.truth.Truth

class Truth(*args: Any, **kwargs: Any)#

Truth data for GT demultiplexing

The truth data is a dataframe with the NGT for each cell and variant

Input and Output#

`read_csv`(csv_file)	Load dna truth from a csv file
`as_input_file`()	Convert the truth to the input file format used by pipelines
`add_doublets`()	Create truth for doublets.

`keep_diff_variants`()	returns: DataFrame of truth
`remove_non_snp_variants`()	Removes indels and spanning deletions from the assignment
`remove_filtered_variants`(dna)	Removes poor quality variants
`remove_correlated_variants`(dna)	Remove correlated variants on the same amplicon
`filter_variants`(dna)	Remove poor quality variants