Dna.mutated_cells

missionbio.mosaic.dna.Dna.mutated_cells

Dna.mutated_cells(labels: Sequence, variants: Optional[Sequence] = None, kind: str = 'count', layer: str = 'NGT_FILTERED') → Series

The count/fraction of cells that are mutated for each clone.

Parameters:

labelsSequence

List of labels for which the mutated cells are to be calculated It must be the same length as the number of cells in the assay.

variantsSequence

List of variants for which the mutated cells are to be calculated for (e.g. [‘chr1:12341234:T/A’]). By default it will get mutated cells for all variants from the assay.

kindstr

The kind of output to return. Can be one of ‘count’ or ‘fraction’. If ‘count’, the number of mutated cells is returned. If ‘fraction’, the fraction of mutated cells is returned.

layerstr

The layer to use for calculating the mutated cells. By default, it will use the NGT_FILTERED layer.

Returns:

mutatedpandas.DataFrame

A dataframe containing the count/fraction of cells that are mutated for each variant.

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< Class Dna