SampleGroup.merge_assay

SampleGroup.merge_assay(assay_name: str = 'dna') → Union[missionbio.mosaic.dna.Dna, missionbio.mosaic.cnv.Cnv, missionbio.mosaic.protein.Protein, missionbio.mosaic.rna.Rna]

Merges an assay across multiple samples into 1 Assay.

Barcodes are renamed to include sample names to avoid clash of barcodes across samples.

A sample group contains a list of samples with assays.

>>> import missionbio.mosaic as ms
>>> grp = ms.load_example_dataset("Multisample PBMC")
>>> [s.dna.title for s in grp]  # Group of assays
['Sample 1', 'Sample 2']

For various analyses data from the assays has to be concatenated. This can be done using the merge_assay command to obtain the _Assay object on which further analysis can be performed.

>>> dna = grp.merge_assay("dna")
>>> dna.title  # A single assay with all the cells
'Sample 1, Sample 2'

Parameters

assay_name:

Which assay to merge. One of {“dna”, “cnv”, “protein”, “rna”}

Returns

Assay:

New assay with combined data from all samples