Dna.get_annotations

Dna.get_annotations(variants: Optional[Sequence] = None) → pandas.core.frame.DataFrame

Annotate DNA variants.

Returns an annotated string array based on the ids of the assay (of form chrA-B-C-D), where A,B,C,D represent the chromosome, position, reference, and alternate variant values of an arbitrary length.

The new strings have a pathological type (PATH, L.PATH, MISS, NONS), and protein or gene added to the beginning of the string. This information is pulled from the MB annotation API.

Parameters

variantslist

List of variant ids to get annotation for (e.g. [‘chr1:12341234:T/A’]). By default it will get annotations for all variants from the assay.

Returns

variantspandas.DataFrame

The array of strings with pathogenicity and gene/protein appended to the front.