Dna¶

class missionbio.mosaic.dna.Dna(*args, **kwargs)¶

Container for DNA data.

Inherits most methods from missionbio.mosaic.assay._Assay. See that for the documentation on other methods and visualizations.

Algorithms

`get_annotations`()	Annotate DNA variants.
`filter_variants`([min_dp, min_gq, min_vaf, …])	Find informative variants.
`filter_variants_consecutive`([proximity])	Remove nearby variants.
`filter_incomplete_barcodes`([barcode_thresh])	Remove cells with missing information.
`find_relevant_variants`([…])	Variants that vary across clusters.
`find_clones`([similarity])	Identify clones based on VAF.
`count`(features[, layer, group_missing, …])	A clustering method available only for DNA.
`cluster_cleanup`(layer[, similarity])	Merge similar clusters while ignoring missing data.

DNA specific visualizations

`plot_variant_correlation`()	The correlation of variants across all cells.
`update_coloraxis`(fig, layer)	Sets the colorscale for DNA.

Extended methods

Mosaic